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c/tapering·posted 1 months ago by u/careful_gradient

tried discontinuation for 13 weeks. here is what happened.

Trial Data Cold Box ×1

tried discontinuation for 13 weeks. here is what happened. Not a hot take, just something I have not seen said plainly here.

The numbers the title promised, since a headline without them is worthless: 13 weeks. Everything below is context for those.

Regained most of it over a year and spent that year assuming it was my fault. It was not; it is what the literature describes.

Went back on after eight months away. Nobody here made me feel bad about it, which mattered more than I expected.

I will update this if the picture changes rather than quietly leaving it up.

1,074 up / 179 down86% upvoted18 commentsid 1cy5mr22 Jun 2026

18 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/priya_guerrero143 points·1 months ago

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

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u/maintenance_mode_maxmaintenance82 points·1 months ago

the habits are what has to carry it afterwards

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u/laila_delgado-33 points·1 months ago

Not convinced. Two weeks of stable weight is not evidence of anything yet.

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u/maren_baptista84 points·1 months ago

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

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u/controversial_only36 points·1 months ago

Same. A quiet fortnight after stopping tells you very little; the interesting part starts later.

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u/border_paperwork24 points·1 months ago

Disagree with the framing. Regain is the documented outcome after discontinuation; calling it a personal failure is both wrong and corrosive.

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u/zeynep_weiss18 points·1 months ago

What is prompting the decision — cost, supply, side effects, or something else?

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u/valeria_cardoso28 points·1 months ago

A written baseline — dose, date, weight, waist, and how appetite feels — taken before any change is what makes the following months interpretable rather than a series of impressions.

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u/nayeli_fonseca23 points·1 months ago

the withdrawal data is unambiguous and it is not about willpower

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u/taper_off_tabithaMOD52 points·1 months ago

Removed the taper schedule written for another member. Describe your own experience instead.

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u/ines_boateng13 points·1 months ago

stretching to ten days then twelve is the pattern people report

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u/careful_gradientOP29 points·1 months ago

Correction: that study measured regain after discontinuation, not loss of effect during treatment. Very different findings.

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u/pavel_halvorsen15 points·1 months ago

Right, and the habits from the losing phase are the part that has to outlive the dose.

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u/honest_syringe_202524 points·1 months ago·edited

stopping is a plan, not an event

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u/yara_bakken18 points·1 months ago

write down where you are before you change anything

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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