[Discussion] the metformin advice in here is 2 years out of date
the metformin advice in here is 2 years out of date, which sounds obvious until you try to state the evidence for it.
Pulling the figures out of the title: 2 years. All of it is written down as it happened rather than reconstructed.
Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.
Incretin-based agents stimulate insulin secretion in a glucose-dependent manner, which is why hypoglycaemia risk with them alone is low. Risk rises with agents that act independently of glycaemia.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
best — the order this archive was captured in
A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.
Left up. It distinguishes the sensor data from the lab result, which most posts here do not.
nothing here replaces the person managing your diabetes
Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.
nothing here replaces the person managing your diabetes
Disagreeing with this line: that endpoint is from the obesity programme and does not answer the question.
Continuous monitoring shows the shape: postprandial excursions, overnight behaviour and time in range. Two people with identical A1c can have very different distributions.
A1c is a three-month average and it lags everything