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c/t2dglp1·posted 7 months ago by u/ingrid_correia

what would you tell week-1 you about glycaemic control

CGM

Asking properly rather than in a comment on somebody else’s thread: what would you tell week-1 you about glycaemic control.

Brought the whole CGM export to my appointment rather than one number. Entirely different conversation.

Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.

Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.

Would rather be corrected in public than confident in private.

323 up / 84 down79% upvoted26 commentsid xiamk124 Dec 2025

26 comments

20 in this archive, depth 6

best — the order this archive was captured in

u/a1c_arcMOD48 points·7 months ago

Identifying details redacted from the exported report above.

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u/kaia_cabrera35 points·7 months ago

Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.

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u/rania_marchand12 points·7 months ago

dose for glycaemic control is not the same conversation as dose for weight

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u/fridge_door_no5 points·7 months ago

A1c is a three-month average and it lags everything

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u/marisol_moreau29 points·7 months ago

Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.

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u/gentle_correctionnice about it24 points·7 months ago

Not convinced. Hypoglycaemia risk from this class alone is low; the risk you are describing comes from the combination.

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u/joaquin_stanescu19 points·7 months ago

That A1c change is inside the assay’s variability and the interval you measured over is too short.

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[deleted]13 points·7 months ago

[deleted]

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u/sigrid_kaufmann11 points·7 months ago

A1c, CGM, or fingersticks — which are we discussing?

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u/zaid_dahlberg3 points·7 months ago

That is a sensor value, not a plasma value, and the two are not interchangeable at that level of precision.

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u/ingrid_correiaOP7 points·7 months ago

Are you quoting a diabetes trial or an obesity one?

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u/tomas_lundgren6 points·7 months ago

This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.

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u/ingrid_correiaOP3 points·7 months ago

What does time in range look like, not just the average?

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u/milan_chukwu1 point·7 months ago

Careful, that is a regimen change suggestion and it needs to come from whoever manages your diabetes.

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u/tired_ledger_notes-9 points·7 months ago

sensor accuracy varies and the first day of a sensor is the worst

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u/cloudy_vial_carol1 point·7 months ago

metformin and an incretin agonist are not in competition

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u/adnan_karlsen10 points·7 months ago

CGM shows you the shape, A1c shows you the area

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u/baseline_drifteranalytical3 points·7 months ago

postprandial excursions are where most of the improvement shows up first

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u/rania_marchand2 points·7 months ago

Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.

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u/santiago_rasmussen6 points·7 months ago

My TSH moved and it turned out to have nothing to do with glucose at all.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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