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c/t2dglp1·posted 5 months ago by u/meal_prep_mira

genuine question about A1c that I am slightly embarrassed to ask

Results Receipts ×8 Slow Clap ×3

Trying to get a straight answer on this: genuine question about A1c that I am slightly embarrassed to ask.

Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.

Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.

Incretin-based agents stimulate insulin secretion in a glucose-dependent manner, which is why hypoglycaemia risk with them alone is low. Risk rises with agents that act independently of glycaemia.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

1,515 up / 192 down89% upvoted25 commentsid woeyz331 Jan 2026

25 comments

3 in this archive, depth 2

best — the order this archive was captured in

u/plain_titration114 points·5 months ago

time in range is the more informative number and it is newer

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u/teodor_duarte70 points·5 months ago

Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.

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u/nadia_norgaard46 points·5 months ago

Yes — time in range tells you about variability, which the average deliberately hides.

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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