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c/t2dglp1·submitted 1 year ago by u/chidi_abubakar

unpopular opinion: most of what gets said here about T2D is guesswork

Cautionbranch of 10 comments

Posting this as a discussion rather than a claim: unpopular opinion: most of what gets said here about T2D is guesswork. Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values. Postprandial excursions…

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10 comments, started 1 year ago
u/runa_grimaldi262 points·1 year ago

Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.

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u/ilias_kaufmann0 points·1 year ago

A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.

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u/gustav_lindholm1 point·1 year ago

A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks.

Agreed, and the glucose-dependence point is the reason the risk profile reads the way it does.

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u/chidi_abubakarOP1 point·1 year ago·edited

Panicked over a first-day sensor reading and rebuilt my week around it. It was the sensor.

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u/gustav_lindholm69 points·1 year ago

How long between the two A1c measurements?

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u/tomas_lokken24 points·1 year ago

How long between the two A1c measurements?

Adding the obvious one — bring the export, not the single number, to whoever manages this.

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u/sanne_laurent16 points·1 year ago

I would not compare your numbers to that population. Different baseline, different regimen, different trial.

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u/gustav_lindholm0 points·1 year ago

I would not compare your numbers to that population.

This is the distinction that resolves most of the confusion here — average versus shape.

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u/fabio_lehtinen1 point·1 year ago

This is the distinction that resolves most of the confusion here — average versus shape.

Disagreeing with this line: that endpoint is from the obesity programme and does not answer the question.

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[deleted]15 points·1 year ago

[deleted]

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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