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c/sideeffects·posted 1 year ago by u/priya_weiss

[Results] 92 weeks, 29kg, and heart rate was the hard part

Discussion Well Actually ×2 Cold Box ×3 Slow Clap ×1

92 weeks, 29kg, and heart rate was the hard part, and the part I actually want to talk about is at the bottom.

Since the title puts numbers in the shop window: 92 weeks and 29kg.

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 16 probably does not, and that is worth saying to a clinician rather than to us.

I will update this if the picture changes rather than quietly leaving it up.

4,483 up / 969 down82% upvoted59 commentsid pxjo4d15 Aug 2024

59 comments

21 in this archive, depth 4

best — the order this archive was captured in

u/britt_abubakar273 points·1 year ago·edited

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.

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u/priya_weiss0 points·1 year ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/enzo_danquah1 point·1 year ago

Pushback: you changed the dose, the meal timing and the training in the same fortnight, so the attribution is guesswork.

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[deleted]1 point·1 year ago

[deleted]

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u/janoshik_junkieindependent tester150 points·1 year ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/nausea_notesMOD104 points·1 year ago

Flair set to Question. Also the standing reminder that nothing on this board is medical advice.

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u/priya_weissOP83 points·1 year ago

reflux at night, try not eating in the three hours before bed

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u/nabila_ogunleye40 points·1 year ago

the first fortnight after a step is the worst of it, then it settles

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u/leila_silva55 points·1 year ago

nobody warns you about how much of this is timing rather than dose

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u/salma_baptista48 points·1 year ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stabl

This is the shape almost everybody here describes, and it is the single most reassuring thing in the thread.

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u/graph_it_gary57 points·1 year ago

write down when it starts and stops, the pattern is the useful part

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u/rekha_mbeki17 points·1 year ago

Nobody warned me about reflux and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

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u/ayesha_radich115 points·1 year ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/aa_analysis_andy94 points·1 year ago

The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.

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u/karma_irrelevant60 points·1 year ago

Not convinced by that mechanism. Slowed gastric emptying explains fullness and reflux; it does not explain what you are describing.

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u/salma_baptista28 points·1 year ago

Mine settled at week 9 and has not come back since, across two more steps.

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u/rekha_mbeki42 points·1 year ago

Careful with the supplement recommendation. There is no evidence for it here and the mechanism you are proposing does not hold.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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