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c/sideeffects·posted 1 year ago by u/isabela_nilsen

reflux — 5 things I got wrong before I got it right

Resolved Well Actually ×6 Clean Column ×1 Receipts ×1

Thinking out loud about this: reflux — 5 things I got wrong before I got it right.

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

fatigue for the first eight days after each step, then nothing, every single time. Predictable enough that I started planning my week around it.

Ask me anything specific. Anything general I will probably get wrong.

3,507 up / 517 down87% upvoted29 commentsid 9vq8ly29 Dec 2024

29 comments

10 in this archive, depth 3

best — the order this archive was captured in

u/reta_and_regret319 points·1 year ago

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.

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u/britt_abubakar142 points·1 year ago

I would be careful here. "Everyone gets this" is not true, and it makes the people who get something unusual assume they are fine when they should be asking.

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u/neha_rahimi65 points·1 year ago

I would be careful here.

Agreed, with the caveat that "usually settles" is not "always settles" and the exceptions should still get asked about properly.

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u/ilias_cabrera210 points·1 year ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/hassan_ostergaard119 points·1 year ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

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u/mikkel_kimani50 points·1 year ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

Disagreeing with this one line: that symptom is not on the wait-and-see list and should not be posted as though it is.

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u/ferran_dahlberg17 points·1 year ago·edited

Disagreeing with this one line: that symptom is not on the wait-and-see list and should not be posted as though it is.

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/quiet_moderatormod86 points·1 year ago

Not convinced by that mechanism. Slowed gastric emptying explains fullness and reflux; it does not explain what you are describing.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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