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185
c/sideeffects·posted 2 months ago by u/fabio_nkemelu

[Discussion] the heart rate advice in here is 2 years out of date

Discussion

the heart rate advice in here is 2 years out of date. Making the case below, and I expect to lose some of it in the comments.

Since the title puts numbers in the shop window: 2 years.

nausea for the first eight days after each step, then nothing, every single time. Predictable enough that I started planning my week around it.

Held the dose for an extra six weeks instead of stepping. The food noise settled and I lost the same amount anyway.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

191 up / 6 down97% upvoted13 commentsid 19nb0w12 May 2026

13 comments

10 in this archive, depth 5

best — the order this archive was captured in

u/brigade_detector45 points·2 months ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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[removed]19 points·2 months ago

[removed by moderator]

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u/aurel_mwangi11 points·2 months ago

I would be careful here. "Everyone gets this" is not true, and it makes the people who get something unusual assume they are fine when they should be asking.

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u/zeynep_zielinski7 points·2 months ago

nobody warns you about how much of this is timing rather than dose

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u/signe_villalobos3 points·2 months ago

Bought four different things to fix my reflux. What actually worked was eating half as fast.

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u/laila_delgado5 points·2 months ago

How long after a step up did this start?

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u/rania_diallo2 points·2 months ago

Pushback: you changed the dose, the meal timing and the training in the same fortnight, so the attribution is guesswork.

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u/coring_the_stopper1 point·2 months ago·edited

eating slower does more than most of the supplements people recommend

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u/long_post_larry25 points·2 months ago·edited

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/ferran_krastev19 points·2 months ago·edited

Severe, or unpleasant? They are genuinely different questions and the answers diverge.

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