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c/semaglutide·posted 8 months ago by u/arne_restrepo

stalled for 22 weeks at 0.5mg and I refuse to panic this time

Discussion Receipts ×8

stalled for 22 weeks at 0.5mg and I refuse to panic this time, and I am aware this is a minority view on this board.

22 weeks and 0.5mg. Those are measured, not estimated, and not rounded up in my favour.

The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

Please do not ask me what dose you should be on. I genuinely do not know and neither does anyone else here.

0 up / 0 down47% upvoted8 commentsid fmxu6q1 Dec 2025

8 comments

8 in this archive, depth 3

best — the order this archive was captured in

u/adnan_karlsen8 points·7 months ago

Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.

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u/source_or_silence6 points·7 months ago

The mental model that finally made this click for me: there are two curves, and people watch the wrong one.

The first is exposure, which is set by the dose and smoothed by a week-long half-life. It changes when you change the dose and then settles over about a month. The second is body weight, which is exposure filtered through appetite, food, water, sleep, training and the scale itself, and which moves in steps rather than a line.

Almost every "it stopped working" post is somebody watching curve two over a fortnight and drawing conclusions about curve one. If the appetite effect is still there, exposure is fine. Wait the month.

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u/salma_vasquez4 points·8 months ago·edited

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/nikhil_teixeira2 points·8 months ago

Sceptical of the mechanism you are proposing. Gastric emptying slows, it does not stop, and the timings you describe do not follow from it.

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u/ravi_sandvik1 point·7 months ago

STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure

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u/archived_thread_a2 points·7 months ago

stalling at 2.4mg is information, not a verdict

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[deleted]3 points·8 months ago

[deleted]

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u/arne_restrepoOP2 points·8 months ago

What did week 83 look like compared with this one? The month either side is the useful comparison.

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