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c/semaglutide·submitted 5 months ago by u/rina_bergstrom

[Discussion] we are measuring Wegovy at the wrong time and calling it noise

Discussionbranch of 9 comments

we are measuring Wegovy at the wrong time and calling it noise. It is the sort of thing everyone half-believes and nobody writes down. Kept a log from week one and the single most useful column turned out to be waist, not weight. nausea made the first fortnight rough at each step up, then flattened out. Predictable…

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9 comments, started 5 months ago
u/alcohol_aversion45 points·5 months ago

STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure

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u/leila_silva16 points·5 months ago

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

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u/kenji_demir23 points·5 months ago

What did week 5 look like compared with this one? The month either side is the useful comparison.

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u/titration_marshalmod · c/semaglutide-18 points·5 months ago

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

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u/hassan_ostergaard5 points·5 months ago

nausea that arrives on day two and fades by day four is the standard shape

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u/nadia_bakker11 points·5 months ago

My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.

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u/arne_amankwah16 points·5 months ago

the first four weeks are a tolerance check, not a weight-loss phase

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u/nadia_bakker22 points·5 months ago

do not chase somebody else’s titration schedule, they are not you

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u/salma_vasquez13 points·5 months ago

Did protein intake change in the same window?

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