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c/semaglutide·posted 4 months ago by u/hassan_ostergaard

is it normal to get early fullness at week 2

Results

is it normal to get early fullness at week 2. This is a description of what happened to me and not a plan for anybody else.

Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.

Would rather be corrected in public than confident in private.

0 up / 0 down42% upvoted5 commentsid br6jz37 Mar 2026

5 comments

5 in this archive, depth 2

best — the order this archive was captured in

u/zofia_lindholm2 points·4 months ago

STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.

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u/ahmed_okafor1 point·4 months ago·edited

My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.

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u/arne_amankwah1 point·4 months ago

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

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u/hassan_ostergaardOP1 point·4 months ago

dose day drift of a day either way is fine, the curve barely notices

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[removed]1 point·4 months ago

[removed by moderator]

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