plateau — 21 things I got wrong before I got it right
plateau — 21 things I got wrong before I got it right. It is the sort of thing everyone half-believes and nobody writes down. Week 54: 15kg down, early fullness basically gone since about week 8, and the honest headline is that nothing dramatic happened. It was boring and it worked. Weight change and appetite change…
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
nausea that arrives on day two and fades by day four is the standard shape
nausea that arrives on day two and fades by day four is the standard shape
Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
Disagree with this specific line. A pause at 1.0mg is not evidence that 1.0mg has stopped working.
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
do not chase somebody else’s titration schedule, they are not you
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
Standard reminder: no personal titration plans for other members, and no medical advice. Everything else is fine.