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c/semaglutide·submitted 2 years ago by u/two_mil_or_one

[Lab] 7th independent test on SSA — 98.9% on a claimed 98.0%, and the trend is the interesting part

Side Effectsbranch of 11 comments

Numbers in the title, numbers in the post. 7th independent test on SSA — 98.9% on a claimed 98.0%, and the trend is the interesting part. Since the title puts numbers in the shop window: 98.9% and 98.0%. My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all. Sat at 2.4mg for four…

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11 comments, started 2 years ago
u/camila_mensa1.4k points·2 years ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/two_mil_or_oneOP0 points·2 years ago

Does reflux track the day after the shot, or is it there all week?

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u/two_mil_or_oneOP1 point·2 years ago·edited

Kept a log from week one and the single most useful column turned out to be waist, not weight.

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u/tomas_kimani1 point·2 years ago

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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u/rohan_steiner648 points·2 years ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes.

Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.

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u/rasmus_kimani181 points·2 years ago

Correct, and worth adding: the trial average is an average. Half the people in it did worse than 15% and were still on the drug.

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u/ines_castellanos0 points·2 years ago

Correct, and worth adding: the trial average is an average.

Disagree with this specific line. A pause at 2.4mg is not evidence that 2.4mg has stopped working.

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u/two_mil_or_oneOP97 points·2 years ago

Week 59: 25kg down, constipation basically gone since about week 9, and the honest headline is that nothing dramatic happened. It was boring and it worked.

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u/niels_lindqvist23 points·2 years ago

Yes — and the honest version is that most of the "it stopped working" posts turn out to be a normal fortnight of water weight.

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u/lane_map_larrylogistics1.1k points·2 years ago

STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.

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u/vikram_mbeki571 points·2 years ago

the scale is the least sensitive instrument you own

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