[Vendor] QYB vs HJ on the same compound, same month — both cleared 99.0%
QYB vs HJ on the same compound, same month — both cleared 99.0%. One vial, one service, one member paying, which is the only kind of result this board should treat as evidence.
99.0%. Those are measured, not estimated, and not rounded up in my favour.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the constipation usually fades at a stable dose.
If somebody has the same thing measured a different way, post it next to mine and we will see whether they agree.
- QYQYB source pageChinaPeptides Co., Ltd. (QYAOBIO) · Shanghai · 93% here, rank 11 · shop at qyaobiopeptides.com →
- HJHJ source pageHubei Jianxiang Bioscience Co., Ltd. · Xianning · 92% here, rank 13 · shop at hubeijianxiang.net →
nofollow and sponsored; nobody here is paid for it.best — the order this archive was captured in
STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.
That reads like a titration plan and this board cannot give you one. Somebody who actually knows your history has to.
Week 18: 6kg down, nausea basically gone since about week 10, and the honest headline is that nothing dramatic happened. It was boring and it worked.
Week 18: 6kg down, nausea basically gone since about week 10, and the honest headline is that nothing dramatic happened.
Disagree with this specific line. A pause at 2.4mg is not evidence that 2.4mg has stopped working.
This matches me almost exactly, right down to the early fullness showing up on the second day and being gone by the fourth.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
Genuine question — is the appetite effect still there, or is it just the scale that has paused?
Did protein intake change in the same window?
the food noise going quiet is the effect people actually describe
protein first, then everything else gets easier
Do muscle cramps track the day after the shot, or is it there all week?
Sceptical of the mechanism you are proposing. Gastric emptying slows, it does not stop, and the timings you describe do not follow from it.
Sceptical of the mechanism you are proposing.
Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.
Are you measuring anything other than weight? Waist is usually the one that keeps moving.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
On the "everybody ends up at 2.4" claim, which comes up every few weeks.
The escalation schedule in the trials was designed to get people to a fixed study dose. Real use is not a trial. The dose that keeps your appetite quiet with side effects you can live with is the dose, and for a lot of people on this board that has been 1.7mg for a very long time.
The counter-argument, which is fair: some people genuinely do need the top of the range, and staying low out of caution costs them months. That is a conversation with someone who knows your history, not with us.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
Minor fix — the half-life is about a week, not about a day. The rest of your point stands.
That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.
if 1.0mg is working there is no prize for going up
Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
I would push back gently. Going up because the scale paused is the single most common mistake described on this board.
staying at 1.7mg for an extra month is a legitimate plan
Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.
Leaving this up. It is a check-in, it has numbers, and it is honest about being one person.
- 1STEP-1 ran 68 weeks and landed just under 15% mean body weight change on…11 comments in this branch · started by u/zeynep_zielinski
- 2Weight change and appetite change are different endpoints on different…8 comments in this branch · started by u/kavya_radich