[Discussion] we talk about dose like it is a score and it is not
Posting this as a discussion rather than a claim: we talk about dose like it is a score and it is not. Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts. Delayed gastric emptying is most pronounced early and…
dose day drift of a day either way is fine, the curve barely notices
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
Correcting myself from earlier in the thread: I said week 5 and it was week 13. Same shape, wrong number.
Correcting myself from earlier in the thread: I said week 5 and it was week 13.
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
Strongly agree on protein. It did more for my constipation than any of the things I bought to fix my constipation.
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.
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Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.
My stall was eleven weeks.
This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
That reads like a titration plan and this board cannot give you one. Somebody who actually knows your history has to.
staying at 2.4mg for an extra month is a legitimate plan
The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.