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c/semaglutide·submitted 1 year ago by u/quiet_moderator

[Discussion] we are measuring plateau at the wrong time and calling it noise

Discussionbranch of 7 comments

Thinking out loud about this: we are measuring plateau at the wrong time and calling it noise. On the "everybody ends up at 2.4" claim, which comes up every few weeks. The escalation schedule in the trials was designed to get people to a fixed study dose. Real use is not a trial. The dose that keeps your appetite…

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7 comments, started 1 year ago
u/ferritin_low363 points·1 year ago

Cosigning. The appetite change and the scale change ran about three weeks apart for me too.

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u/prior_auth_painappeals92 points·1 year ago

Same injection day each week, or has it drifted?

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u/marta_trevino37 points·1 year ago

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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[deleted]15 points·1 year ago

[deleted]

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u/dead_space_doug18 points·1 year ago·edited

Strongly agree on protein. It did more for my fatigue than any of the things I bought to fix my fatigue.

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u/quiet_moderatorOPmod0 points·1 year ago

Are you measuring anything other than weight? Waist is usually the one that keeps moving.

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u/ffmi_watcher1 point·1 year ago

That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.

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