what would you tell week-1 you about Wegovy
what would you tell week-1 you about Wegovy — that is what I am asking, and I have already read the wiki twice.
STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.
Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
Week 91: 34kg down, early fullness basically gone since about week 8, and the honest headline is that nothing dramatic happened. It was boring and it worked.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
best — the order this archive was captured in
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.
Sceptical of the mechanism you are proposing. Gastric emptying slows, it does not stop, and the timings you describe do not follow from it.
Are you measuring anything other than weight? Waist is usually the one that keeps moving.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
the food noise going quiet is the effect people actually describe
What did week 31 look like compared with this one? The month either side is the useful comparison.
the scale is the least sensitive instrument you own
Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.
Careful.
vikram_ferreira is describing the standard shape here and it matches the trial data better than most anecdotes do.
Genuine question — is the appetite effect still there, or is it just the scale that has paused?
if 2.4mg is working there is no prize for going up