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c/semaglutide·submitted 1 year ago by u/greta_perrin

[Results] 96 weeks, 40kg, and 2.4mg was the hard part

Resultsbranch of 11 comments

Six-word version is the title — 96 weeks, 40kg, and 2.4mg was the hard part — and the rest is context. The relevant figures are 96 weeks, 40kg and 2.4mg, and they come from the same log I have kept the whole time. Sat at 1.7mg for four months because it was doing the job. Everyone told me to go up. The one time I…

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11 comments, started 1 year ago
u/coa_janitormod · c/coa383 points·1 year ago

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

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u/yara_boateng517 points·1 year ago

Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.

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u/aleksi_grimaldi184 points·1 year ago

Strongly agree on protein. It did more for my muscle cramps than any of the things I bought to fix my muscle cramps.

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u/greta_perrinOP105 points·1 year ago

if 0.25mg is working there is no prize for going up

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u/katrin_diallo59 points·1 year ago

fatigue made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it.

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u/niels_lindqvist15 points·1 year ago

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

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u/marit_coelho22 points·1 year ago

Dropped my injection day by two days once because of travel. Nothing happened. The panic was worse than the effect.

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u/zofia_lindholm0 points·1 year ago

the first four weeks are a tolerance check, not a weight-loss phase

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u/two_mil_or_one-8 points·1 year ago

2.4 is a ceiling, not a target

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u/rafael_ostergaard1 point·1 year ago·edited

the food noise going quiet is the effect people actually describe

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[deleted]1 point·1 year ago

[deleted]

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