[Vendor] CPC vs MKM on the same compound, same month — both cleared 97.5%
Filing this under things worth writing down: CPC vs MKM on the same compound, same month — both cleared 97.5%.
To save the first four comments: 97.5%.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
- MKMKM source pageXi'an Mokemei Biotechnology Co., Ltd. · Xi'an · 96% here, rank 5 · shop at mokemeibiotechnology.com →
- CPCPC source pageChinese Peptide Company Co., Ltd. · Hangzhou · 93% here, rank 12 · shop at chinesepeptidecompany.net →
nofollow and sponsored; nobody here is paid for it.best — the order this archive was captured in
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.
That reads like a titration plan and this board cannot give you one. Somebody who actually knows your history has to.
protein first, then everything else gets easier
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
Yes. Week 45 is when almost everybody writes the "is it still working" post, and almost everybody is fine.
nausea that arrives on day two and fades by day four is the standard shape
stalling at 2.4mg is information, not a verdict
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the sulphur burps usually fades at a stable dose.
Retitled to match the body. The original promised a comparison the post does not make.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
do not chase somebody else’s titration schedule, they are not you
Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.