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c/retatrutide·submitted 3 months ago by u/ismael_eriksen

someone explain retatrutide to me like I have not read a paper in years

Labbranch of 7 comments

someone explain retatrutide to me like I have not read a paper in years. I would rather ask a basic question now than get this wrong quietly for two months. Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects. That is a mechanistic story with strong preclinical support…

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7 comments, started 3 months ago

u/emil_agyeman563 points·3 months ago

research-use-only material is not approved for human use, full stop

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u/ismael_eriksenOP263 points·3 months ago

Stopped at a low step because there was no reason to go further and no data to tell me what further would do.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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