[Lab] 2th independent test on BCH — 97.8% on a claimed 97.5%, and the trend is the interesting part
Title says it — 2th independent test on BCH — 97.8% on a claimed 97.5%, and the trend is the interesting part — so here is the boring supporting detail that makes it worth anything. The relevant figures are 97.8% and 97.5%, and they come from the same log I have kept the whole time. Watched heart rate on a wearable…
Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects. That is a mechanistic story with strong preclinical support and limited phase 2 human data.
Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects.
employer_carveout is right about the escalation being the variable. It explains most of the difficult reports here.
The phase 2 readout ran to 48 weeks in a few hundred participants with a slow escalation. Both the size and the duration matter when people quote the headline number.
Cosigning the escalation point. Almost every difficult report on this board is from somebody who went up quickly.
nothing here is available as a prescription product, so read every thread with that in mind
What do you think the glucagon component is adding, specifically?
It is a triple agonist at the GLP-1, GIP and glucagon receptors. The glucagon arm is the genuinely novel component and it is the one with the least human outcome data behind it.