[Discussion] dose-response looked steeper than anything else in the class and that cuts both ways
I have had 11 orders now and I keep a table, so here is the honest summary rather than a vibe.
Material has been consistent. Communication has not. Shipping has varied by about 18 days on nominally the same lane, which matters more in summer than in February.
The independent number came back 96.8% against a claimed 99.1%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.
Batch number is in the comments. Ask if you want the method.
best — the order this archive was captured in
the glucagon component changes the side effect profile, not just the efficacy
Flair changed to match the content. Read the sidebar before posting next time and we are square.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
nobody should be giving this to anyone without extensive monitoring
What was the dosing schedule in that arm?
the 2.5mg arm is different from 2.4mg, results do not transfer
the weight curves are unusually steep, which makes predicting individual response harder
Strongly agree. Heart rate escalation needs the actual data, not impressions.
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
phase 2 numbers are not maintenance numbers, cite the trial
This is correct. Triple agonism is genuinely different.
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Mechanistically the bit that matters is TRIUMPH. It explains most of the early profile and a decent chunk of the outcome.
This is correct. Triple agonism is genuinely different.
nobody should be giving this to anyone without extensive monitoring
- 1What was the dosing schedule in that arm?7 comments in this branch · started by u/iman_castellanos