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c/retatrutide·posted 5 days ago by u/source_or_silence

the glucagon arm is why the appetite effect feels different

Question Cold Box ×1 Slow Clap ×3

Right, the triple agonist question again, but with numbers this time.

I have 17 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 16, not week 65. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

1,143 up / 178 down87% upvoted36 commentsid 1lgwl724 Jul 2026

36 comments

6 in this archive, depth 2sorted by:

best — the order this archive was captured in

u/reta_and_regretMOD173 points·5 days ago

Retitled to remove editorialising. Put the evidence in the body.

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u/andres_sorensen118 points·4 days ago

Which trial arm and what was the n?

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u/matias_falk141 points·5 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/halima_mbeki104 points·4 days ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/marit_laurent0 points·4 days ago

fair enough

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u/mateusz_mensah1 point·3 days ago

research use only, handling and analysis, not protocols

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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More in c/retatrutide

1[Results] 2 weeks, 46kg, and phase 2 was the hard part14k points · 45 comments
2switched from 2.5mg to 10mg and the early fullness got better, not worse13k points · 37 comments
3glucagon — my 7-week log, condensed into one table12k points · 37 comments
4what changed for me between week 65 and week 1312k points · 35 comments
5[Results] 37 weeks, 16kg, and phase 2 was the hard part9.9k points · 50 comments
6unpopular opinion: retatrutide is massively overrated8.7k points · 68 comments

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