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c/retatrutide·posted 7 days ago by u/nadia_trevino

is anyone tracking heart rate properly on reta or are we all guessing

Discussion Cold Box ×7

Quick one. Canada here.

glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 16 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

654 up / 117 down85% upvoted19 commentsid 1kwxdt23 Jul 2026

19 comments

12 in this archive, depth 4

best — the order this archive was captured in

u/discount_math_dm-23 points·6 days ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/isabela_nilsen1 point·5 days ago

the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet

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u/ismael_eriksen32 points·5 days ago

nobody should be giving this to anyone without extensive monitoring

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u/reta_and_regretMOD16 points·5 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/lane_watchermod · logistics13 points·5 days ago

What was the dosing schedule in that arm?

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u/dead_space_doug13 points·5 days ago

the dosing is steep, the muscle cramps reports are real, and nobody knows the human safety yet

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u/source_or_silence8 points·5 days ago

Slight fix: the number was 99.1, not 93.7. Decimal point, but a fairly consequential one.

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u/careful_gradient_notes15 points·5 days ago

This is correct. Triple agonism is genuinely different.

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u/nadia_trevinoOP9 points·5 days ago

Respectfully this is a sample of one presented as a finding.

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u/andres_sorensen8 points·5 days ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/burned_once_twice6 points·5 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/trialwatch_theotrial nerd2 points·4 days ago

the glucagon component changes the side effect profile, not just the efficacy

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
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