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c/retatrutide·submitted 4 days ago by u/sena_teixeira

[Caution] this is not approved anywhere and half this community forgets that

Cautionbranch of 8 comments

Week 23 update. 4kg down from the start, muscle cramps basically gone since about week 63. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps. The part that surprised me is how much of this is admin.…

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8 comments, started 2 days ago
u/lane_watchermod · logistics58 points·2 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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[deleted]41 points·1 days ago

[deleted]

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u/marit_laurent24 points·1 days ago

research use only, handling and analysis, not protocols

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u/incretin_ivypharmacology9 points·1 days ago·edited

phase 2 numbers are not maintenance numbers, cite the trial

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u/andres_restrepo40 points·1 days ago

triple agonism is phase 2, do not generalise

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u/sena_teixeiraOP18 points·1 days ago

The glucagon component does different things than dual agonism. The early fullness are not just amplified versions.

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u/ewan_marchand17 points·1 days ago·edited

the weight curves are unusually steep, which makes predicting individual response harder

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u/sena_teixeiraOP-14 points·1 days ago

What was the dosing schedule in that arm?

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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