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c/retatrutide·posted 4 days ago by u/sena_teixeira

[Caution] this is not approved anywhere and half this community forgets that

Caution Clean Column ×5

Week 23 update. 4kg down from the start, muscle cramps basically gone since about week 63.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

855 up / 176 down83% upvoted20 commentsid 1jsyz126 Jul 2026

20 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/freya_baptista126 points·2 days ago

The glucagon component does different things than dual agonism. The injection-site soreness are not just amplified versions.

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u/sena_teixeiraOP60 points·2 days ago

You have restated the marketing copy. What is the actual substance here.

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u/cold_chromatogram_only108 points·4 days ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/injection_site_iris52 points·3 days ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/lane_watchermod · logistics58 points·2 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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[deleted]41 points·1 days ago

[deleted]

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u/marit_laurent24 points·1 days ago

research use only, handling and analysis, not protocols

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u/incretin_ivypharmacology9 points·1 days ago·edited

phase 2 numbers are not maintenance numbers, cite the trial

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u/andres_restrepo40 points·1 days ago

triple agonism is phase 2, do not generalise

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u/sena_teixeiraOP18 points·1 days ago

The glucagon component does different things than dual agonism. The early fullness are not just amplified versions.

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u/ewan_marchand17 points·1 days ago·edited

the weight curves are unusually steep, which makes predicting individual response harder

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u/sena_teixeiraOP-14 points·1 days ago

What was the dosing schedule in that arm?

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.