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[Discussion] the research peptides advice in here is 3 years out of date

Discussionbranch of 8 comments

the research peptides advice in here is 3 years out of date. I have gone back and forth on this for months. 3 years — those are the numbers, and they are the ones I am willing to defend. Storage conditions came back specific rather than generic when I asked. That told me somebody had actually done stability work.…

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8 comments, started 4 months ago
u/chain_confirm_cpayments8 points·4 months ago

Why purity and net content diverge, and why that is usually honest.

Purity by area percent is a relative measure of what the detector saw. Net peptide content subtracts counterion, water and residual solvent from the powder mass. For some compounds in this catalogue the gap between the two is large.

A vial can therefore be 99% pure and contain considerably less peptide by mass than the label weight suggests, with nothing wrong anywhere. The problem is not the chemistry; it is that people compare a purity figure from one supplier with a net content figure from another and conclude something about both. Ask which number you are being shown, every time.

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u/heart_rate_bump3 points·4 months ago

catalogue depth is not the same as catalogue quality

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u/cold_chromatogram_onlyOP9 points·4 months ago

Asked GL Biochem which lines they keep in regional stock versus make to order and got a clear split. It changed what I ordered.

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u/throwaway_wl202611 points·4 months ago

Agreed that thin testing here says something about the members, not about the material.

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u/old_account_20233 points·4 months ago

lyophilised and stored cold is the default for a reason

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[removed]1 point·4 months ago

[removed by moderator]

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u/honest_syringe1 point·4 months ago

ask which lines are actually stocked rather than made to order

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u/erez_yilmaz2 points·4 months ago

lyophilised and stored cold is the default for a reason

old_account_2023 is right that a purity figure without a method is not comparable to one with a method.

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