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c/reconstitution·submitted 5 days ago by u/ilias_cabrera

[Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not

Explainerbranch of 8 comments

why 1mL syringes cause overdoses and 0.3mL ones do not. If you already knew this, the post is not for you and you can scroll on. 1mL and 0.3mL. Those are measured, not estimated, and not rounded up in my favour. Spent 17 weeks confused about this until somebody drew the table for me. 5mg, 1mL, 5mg/mL, 2mg is 40…

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8 comments, started 3 days ago
u/nadia_kjaer54 points·3 days ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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u/piotr_bruun14 points·3 days ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose.

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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u/ilias_cabreraOP7 points·3 days ago·edited

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/quarter_dose_queenlow and slow10 points·3 days ago

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

piotr_bruun has the units point exactly right. They are a volume on the barrel and nothing else.

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u/RetaAndRegret26 points·3 days ago

dead space in the needle hub is real and it is small

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u/saskia_rahimi5 points·3 days ago

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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[deleted]40 points·3 days ago

[deleted]

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u/janek_ferrari32 points·3 days ago

Show the arithmetic — where did the unit figure come from?

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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