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c/reconstitution·submitted 2 years ago by u/janek_ferrari

[Meta] proposal — a flair for units posts

PSAbranch of 9 comments

proposal — a flair for units posts, and it will stay as it is unless somebody makes the case to change it. I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume. Research-use-only material is not approved for human use, so treat everything in…

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9 comments, started 2 years ago
u/sock_puppet_spotter521 points·2 years ago

Asked GGPeps what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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u/bac_water_banditMOD344 points·2 years ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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u/emil_zamora507 points·2 years ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/anjali_tamm198 points·2 years ago

a U-100 syringe reads 100 units to the millilitre, every time

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u/batch_number_bertievetting211 points·2 years ago

Working has to be shown on arithmetic posts.

Right, and the arithmetic behind it: 30mg in 3mL is 10mg/mL, so 2.5mg is 25 units.

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u/rina_bergstrom136 points·2 years ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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u/swirl_dont_shakereconstitution158 points·2 years ago

Spent 13 weeks confused about this until somebody drew the table for me. 15mg, 3mL, 5mg/mL, 0.5mg is 10 units. That is the whole thing.

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u/janek_ferrariOP254 points·2 years ago

Working has to be shown on arithmetic posts.

bac_water_bandit has the units point exactly right. They are a volume on the barrel and nothing else.

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u/adaeze_cabrera254 points·2 years ago

I would not round that figure. At 5mg/mL a rounding error of two units is a real fraction of the intended amount.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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  1. Show your numbers. "How many units?" with no mg and no mL cannot be answered.
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