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c/reconstitution·submitted 7 months ago by u/swirl_dont_shake

the dead space thing finally clicked for me and I want to write it down

Discussionbranch of 6 comments

Posting this as a discussion rather than a claim: the dead space thing finally clicked for me and I want to write it down. Why "more water" keeps confusing people, including me for a month. The vial contains a fixed amount of peptide. Water changes nothing about that amount. What it changes is concentration, and…

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6 comments, started 7 months ago
u/andres_sorensen26 points·7 months ago

Yes. Writing 10mg/mL on the vial takes four seconds and removes the entire class of error this board exists to fix.

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u/wanjiru_varga20 points·7 months ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/nabila_espinoza9 points·7 months ago

10mg into 2mL is 5mg/mL, and 0.75mg of that is 15 units

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u/niels_roos6 points·7 months ago

if the maths gives you a fraction of a unit, change the concentration

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u/tl_dr_tina10 points·7 months ago

Agreed on the swirl. There is no reason to shake it and a good reason not to.

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u/vial_math_verasyringe math6 points·7 months ago

aim the stream at the glass wall, not at the cake

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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