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c/reconstitution·submitted 3 months ago by u/hub_ops

unpopular opinion: most of what gets said here about bacteriostatic water is guesswork

Questionbranch of 6 comments

The title is the argument: unpopular opinion: most of what gets said here about bacteriostatic water is guesswork. Here is the rest of it. Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero. The dead space question sent me down a rabbit hole for a week. It is…

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6 comments, started 3 months ago
u/units_not_mgsyringe math7 points·3 months ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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u/hub_opsOPsite staff3 points·3 months ago·edited

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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u/india_generic_g2 points·3 months ago

Correction: that gives 15 units, not what you have written. 10mg into 2mL is 5mg/mL and the division follows from there.

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u/bac_water_banditreconstitution1 point·3 months ago

more water is not more drug, it is the same drug in a bigger volume

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u/hub_opsOPsite staff2 points·3 months ago

Are you accounting for the powder volume, or is that where the confusion is?

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u/priya_weiss3 points·3 months ago

Cosigning the round-number approach. Reconstituting to something awkward is how you end up drawing 27.5 units at six in the morning.

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The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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