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c/reconstitution·submitted 4 months ago by u/viktor_erdogan

three years of dead space threads, summarised so you do not have to read them

Correctionbranch of 8 comments

three years of dead space threads, summarised so you do not have to read them. Not a hot take, just something I have not seen said plainly here. Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire…

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8 comments, started 4 months ago
u/india_generic_g45 points·4 months ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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u/bac_water_banditreconstitution36 points·4 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/cardio_endpoint_c17 points·4 months ago

units are a volume on a U-100 syringe, not a dose

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u/arto_falk22 points·4 months ago·edited

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable.

This is the sentence that makes the rest unnecessary. Write it on the vial and the problem is gone.

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u/arne_restrepo26 points·4 months ago

reconstituting at a round concentration makes every later dose easy

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u/kavya_radich51 points·4 months ago

more water is not more drug, it is the same drug in a bigger volume

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u/kenji_kimani28 points·4 months ago

That is sterile water, not bacteriostatic. Same appearance, different product, and it matters for a multi-draw vial.

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u/nadia_kjaer38 points·4 months ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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