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c/reconstitution·submitted 9 months ago by u/quiet_reader_99

[Meta] proposal — a flair for reconstitution posts

Questionbranch of 11 comments

proposal — a flair for reconstitution posts — posting the reasoning in public because a policy you cannot inspect is just a preference. Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since. Wrote the date on the vial as well as the concentration after losing track of…

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11 comments, started 9 months ago
u/ahmed_rasmussen36 points·9 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/ines_ekstrom20 points·9 months ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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u/quiet_reader_99OP28 points·9 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable.

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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[deleted]11 points·9 months ago

[deleted]

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u/saskia_rahimi8 points·9 months ago

a U-100 syringe reads 100 units to the millilitre, every time

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u/honest_syringe_20257 points·9 months ago·edited

Same. I got this wrong once, caught it because the units looked absurd, and have written on every vial since.

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u/quiet_reader_99OP21 points·9 months ago

What is written on the vial right now?

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u/vito_beaulieu5 points·9 months ago·edited

Is that a U-100 syringe? The barrel markings change the answer completely.

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u/bac_water_banditreconstitution8 points·9 months ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/quiet_reader_99OP0 points·9 months ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/niels_roos0 points·9 months ago·edited

That is sterile water, not bacteriostatic. Same appearance, different product, and it matters for a multi-draw vial.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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