reconstituted at 1mL instead of 2mL and caught it before injecting. lucky.
Genuinely asking, not being difficult.
Everyone in c/cagrilintide repeats that dead space is important. I believe it, but I have never seen anyone show why, and when I search I get 9 threads of people agreeing with each other.
Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?
I am not trying to be the "source?" guy. I would just like a source.
best — the order this archive was captured in
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
I am going to push back on this slightly.
Retitled to remove editorialising. Put the evidence in the body.
This is correct. 1mL versus 4mL is the common mistake.
dosing errors come from people reconstituting two vials differently and forgetting which is which
What was the vial size and how much bac water?
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Disagree. What you are describing is consistent with concentration, not with what you concluded.
never post a calculation as advice without stating the concentration
swirl, do not shake, or you are courting oxidation
u-100 syringe, not u-40, or your math is off by factor of 7
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Yes, exactly this, and it is the bit that took me 7 weeks to accept.
Cosigning. The concentration on the vial in marker is load-bearing.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
u-100 syringe, not u-40, or your math is off by factor of 10
dead space is real and the syringe matters
Cosigning. The concentration on the vial in marker is load-bearing.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
stopper coring on the 3th draw because you keep using the same entry point. rotate.
stopper coring on the 3th draw because you keep using the same entry point.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
bacteriostatic and sterile water are not interchangeable, do not use them that way
the concentration on the vial in marker is the most important step
Is that 30mg vial or 24mg?
Dead space ate 3 units on a low-volume draw. Tiny impact at 1.0mg, massive impact at 0.5mg.
Titration speed is a side-effect dial far more than an efficacy dial.
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I am going to push back on this slightly.
stopper coring on the 10th draw because you keep using the same entry point. rotate.
never post a calculation as advice without stating the concentration
- 1Every time this gets posted it hits the front page and every time someone…16 comments in this branch · started by u/sleep_apnea_sam
- 2Titration speed is a side-effect dial far more than an efficacy dial.5 comments in this branch · started by u/emeka_delgado