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Single comment threadYou are looking at one branch of the insulin syringe thing finally clicked for me and I want to write it down — 39 comments in the full submission. View in context.
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c/reconstitution·submitted 1 year ago by u/sofia_danquah

the insulin syringe thing finally clicked for me and I want to write it down

Discussionbranch of 9 comments

the insulin syringe thing finally clicked for me and I want to write it down, which sounds obvious until you try to state the evidence for it. Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person. I keep a…

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9 comments, started 12 months ago
u/ines_lindqvist22 points·12 months ago

write the concentration on the vial in marker, that is the whole post

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u/rasmus_kuipers17 points·12 months ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/lurker_for_years18 points·12 months ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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u/honest_syringe_maybe18 points·12 months ago

a U-100 syringe reads 100 units to the millilitre, every time

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u/andres_sorensen6 points·12 months ago

units are a volume on a U-100 syringe, not a dose

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u/dilara_szabo9 points·12 months ago

more water is not more drug, it is the same drug in a bigger volume

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u/signe_grimaldi4 points·12 months ago·edited

more water is not more drug, it is the same drug in a bigger volume

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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u/nadia_kjaer18 points·12 months ago

reconstituting at a round concentration makes every later dose easy

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u/ruben_cabrera11 points·12 months ago

reconstituting at a round concentration makes every later dose easy

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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