units — 21 things I got wrong before I got it right
Thinking out loud about this: units — 21 things I got wrong before I got it right. The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw. Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.…
Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.
Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.
Spent 10 weeks confused about this until somebody drew the table for me. 10mg, 2mL, 5mg/mL, 0.5mg is 10 units. That is the whole thing.
Asked SSA what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.
if the maths gives you a fraction of a unit, change the concentration
Pushback on the syringe advice: a U-100 barrel reads units of volume. Calling them "doses" is how the confusion starts.
Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since.