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c/reconstitution·submitted 1 year ago by u/santiago_ndiaye

do units actually matter or is it forum lore at this point

Questionbranch of 10 comments

Asking properly rather than in a comment on somebody else’s thread: do units actually matter or is it forum lore at this point. Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful. Reconstituted at…

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10 comments, started 1 year ago
u/marta_weiss271 points·1 year ago

reconstituting at a round concentration makes every later dose easy

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u/nabila_espinoza122 points·1 year ago

reconstituting at a round concentration makes every later dose easy

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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u/sleep_apnea_sam185 points·1 year ago

units are a volume on a U-100 syringe, not a dose

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u/santiago_ndiayeOP159 points·1 year ago

Correction: that gives 30 units, not what you have written. 10mg into 3mL is 3.33mg/mL and the division follows from there.

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u/mateusz_achebe213 points·1 year ago

label the vial with the date as well as the concentration

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[removed]152 points·1 year ago

[removed by moderator]

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u/santiago_ndiayeOP111 points·1 year ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/spain_receta64 points·1 year ago

5mg into 1mL is 5mg/mL, and 0.75mg of that is 15 units

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u/priya_guerrero33 points·1 year ago

Cosigning the round-number approach. Reconstituting to something awkward is how you end up drawing 27.5 units at six in the morning.

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u/emil_okwuosa26 points·1 year ago

the number you write down is the number you will trust at 6am

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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