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c/reconstitution·submitted 1 months ago by u/elin_ferrari

[Discussion] insulin syringe is doing more work than we give it credit for

Discussionbranch of 9 comments

The title is the argument: insulin syringe is doing more work than we give it credit for. Here is the rest of it. Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero. The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and…

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9 comments, started 1 months ago
u/hedda_ekstrom218 points·1 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/mateusz_achebe132 points·1 months ago·edited

Spent 13 weeks confused about this until somebody drew the table for me. 20mg, 2mL, 10mg/mL, 5mg is 50 units. That is the whole thing.

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u/emil_zamora34 points·1 months ago

the number you write down is the number you will trust at 6am

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u/honest_syringe_maybe24 points·1 months ago

Asked GGPeps what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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u/alcohol_aversion7 points·1 months ago

dead space in the needle hub is real and it is small

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u/rasmus_mensah5 points·1 months ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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