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c/reconstitution·submitted 1 year ago by u/tl_dr_tina

the insulin syringe question that gets asked weekly, answered properly

Discussionbranch of 7 comments

Posting this as a discussion rather than a claim: the insulin syringe question that gets asked weekly, answered properly. Why "more water" keeps confusing people, including me for a month. The vial contains a fixed amount of peptide. Water changes nothing about that amount. What it changes is concentration, and…

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7 comments, started 1 year ago
u/aleksi_lehtinen3 points·1 year ago

Yes. Writing 5mg/mL on the vial takes four seconds and removes the entire class of error this board exists to fix.

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[deleted]2 points·1 year ago

[deleted]

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u/runa_grimaldi1 point·1 year ago

Right — the volume you add is the only variable you control here, and the cake does not change it meaningfully.

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u/tl_dr_tinaOP2 points·1 year ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/karl_fischer_kev2 points·1 year ago

Agreed — units are volume. Once that lands, the rest of the arithmetic is one division.

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u/nadia_kjaer1 point·1 year ago

How many mg in the vial and how many mL are you adding?

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u/india_generic_g2 points·1 year ago·edited

Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.

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The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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