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c/orforglipron·submitted 8 months ago by u/piotr_bruun

[Lab] 15th independent test on WXT — 99.4% on a claimed 98.5%, and the trend is the interesting part

Questionbranch of 9 comments

15th independent test on WXT — 99.4% on a claimed 98.5%, and the trend is the interesting part, and before anyone asks: same batch throughout, single submission, no cherry-picking between services. 99.4% and 98.5% — those are the numbers, and they are the ones I am willing to defend. The no-timing-restriction thing…

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This branch

9 comments, started 8 months ago
u/phase_two_peteMOD57 points·8 months ago

Corrected a cross-class dose comparison in the title. The body is untouched.

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u/phase_two_pete19 points·8 months ago

Yes — nothing containing this is approved anywhere, and the threads keep forgetting it.

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u/scam_taxonomyc/scamalerts21 points·8 months ago

That is a phase 2 result being quoted as though the programme had reported.

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u/sanne_delgado13 points·8 months ago

Daily dosing gives a very different exposure profile from a weekly injectable: peaks and troughs within each day rather than a smoothed weekly curve.

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u/piotr_bruunOP8 points·8 months ago

Correction: that is the oral peptide product, which is a different thing entirely. This one is a small molecule.

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u/blank_injection0 points·8 months ago

Correction: that is the oral peptide product, which is a different thing entirely.

This is the fact the whole board hangs on. Small molecule, not peptide.

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u/lina_bruun6 points·8 months ago

phase 3 is where the comparison becomes fair

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u/camila_vasquez46 points·8 months ago

Small fix — the two programme names got swapped upthread and it changes which population the figure came from.

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u/piotr_bruun38 points·8 months ago

the manufacturing story is genuinely different from the injectables

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