[Lab] 15th independent test on WXT — 99.4% on a claimed 98.5%, and the trend is the interesting part
15th independent test on WXT — 99.4% on a claimed 98.5%, and the trend is the interesting part, and before anyone asks: same batch throughout, single submission, no cherry-picking between services. 99.4% and 98.5% — those are the numbers, and they are the ones I am willing to defend. The no-timing-restriction thing…
What is actually known, and what is being assumed.
Known: it is a small-molecule GLP-1 receptor agonist, dosed daily, with clinical programmes reporting in both obesity and type 2 diabetes. Its tolerability profile broadly resembles the class in the data published so far.
Assumed, frequently and confidently: that milligram comparisons with injectables mean something, that adherence is straightforwardly better because it is a tablet, that peptide purity discussions transfer to it. None of those hold. And nothing containing this compound is approved anywhere, which makes research-use-only material exactly that — not approved for human use.
Yes. Oral peptide with an absorption enhancer and oral small molecule are completely different propositions.
Disagree. You are comparing doses across a small molecule and a peptide, which is not a comparison of anything.
Disagree.
Disagreeing with this bit: daily dosing is a different adherence problem, not a better one.
Holding off on any opinion until phase 3 reports. That is not a satisfying position and it is the honest one.
Phase 2 or phase 3?
Milligram-for-milligram comparison with an injectable peptide is not meaningful and I should not have made it.
Same view. The analytical problem is different enough that the usual purity discussions here do not transfer cleanly.
the boards keep comparing it to injectables at matched doses, which is meaningless