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c/orforglipron·posted 11 days ago by u/muscle_cramp_mo

[Paper] ACHIEVE-1 glycaemic data vs the injectables

Paper Receipts ×4

Something I noticed reading old threads that I have not seen said out loud.

The advice on ATTAIN in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

346 up / 41 down89% upvoted23 commentsid ntsr8x18 Jul 2026

23 comments

16 in this archive, depth 4

best — the order this archive was captured in

u/deleted_my_history54 points·10 days ago

The nausea was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/scam_taxonomyc/scamalerts18 points·10 days ago

Second this question. I have wondered about non-peptide for 8 months and never seen a straight answer.

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u/lukas_delgado7 points·10 days ago

the supply conversation changes if this approves

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u/camila_vasquez45 points·10 days ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/first_hundred36 points·10 days ago

small molecule, not a peptide, purity discussion is different

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u/muscle_cramp_moOP20 points·9 days ago

The the food-noise thing was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/phase_two_pete16 points·10 days ago

phase 10 data is interesting, phase 38 will tell the real story

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u/zeynep_ndiaye28 points·10 days ago

ATTAIN and ACHIEVE are phase 18 trials

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u/aksel_kjaer18 points·10 days ago

cite ATTAIN/ACHIEVE arms specifically

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u/reship_roulette5 points·10 days ago

Did anything else change in the same window?

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u/marit_sandvik14 points·10 days ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/phase_two_peteMOD8 points·9 days ago·edited

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/trialwatch_theotrial nerd12 points·9 days ago·edited
good post. terrible flair.
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u/kenji_laurent3 points·9 days ago

This is correct. ATTAIN data is phase 11.

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[removed]1 point·9 days ago

[removed by moderator]

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u/hazard_ratio_halstats1 point·9 days ago

That is net peptide content, not purity. Different number, different meaning.

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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c/orforglipron rules
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