[Lab] QYB orfo — Medutest came back 99.2% against a claimed 99.0%
QYB orfo — Medutest came back 99.2% against a claimed 99.0%. One vial, one service, one member paying, which is the only kind of result this board should treat as evidence.
99.2% and 99.0% — those are the numbers, and they are the ones I am willing to defend.
Oral semaglutide is a peptide co-formulated with an absorption enhancer and carries food and water timing requirements. A small molecule does not have that constraint, which is the practical distinction.
Daily dosing gives a very different exposure profile from a weekly injectable: peaks and troughs within each day rather than a smoothed weekly curve.
Tell me where this is wrong. That is the useful part of posting it.
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nofollow and sponsored; nobody here is paid for it.best — the order this archive was captured in
Left up. It is careful about what is peptide and what is not, which is more than most threads here manage.
oral semaglutide is a peptide with an absorption enhancer, this is not that
Push back: daily dosing is not automatically better adherence. It is a different failure mode, not a solved problem.
Milligram-for-milligram comparison with an injectable peptide is not meaningful and I should not have made it.
daily dosing changes adherence in both directions
Disagree. You are comparing doses across a small molecule and a peptide, which is not a comparison of anything.
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Is that from the publication or the press release?
Agreed — non-peptide is the fact that everything else follows from, including the manufacturing and the analytics.
Because it is not a peptide, it is not subject to the same degradation pathways, does not require the absorption enhancers used for oral peptides, and can be formulated as a conventional tablet.
Went looking for independent testing on this and found essentially nothing, which was clarifying.
Read both programme names carefully after mixing them up in a comment and being politely corrected.
Correction: that is the oral peptide product, which is a different thing entirely. This one is a small molecule.
do not assume reconstitution intuitions apply, there is nothing to reconstitute
- 1Left up. It is careful about what is peptide and what is not, which is more…9 comments in this branch · started by u/phase_two_pete