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c/orforglipron·submitted 1 months ago by u/neha_krastev

help me understand non-peptide, I have read the wiki twice

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Trying to get a straight answer on this: help me understand non-peptide, I have read the wiki twice. Went looking for independent testing on this and found essentially nothing, which was clarifying. Read both programme names carefully after mixing them up in a comment and being politely corrected. The…

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8 comments, started 1 months ago
u/pancreatitis_scare53 points·1 months ago

Daily dosing gives a very different exposure profile from a weekly injectable: peaks and troughs within each day rather than a smoothed weekly curve.

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u/neha_krastevOP28 points·1 months ago

the tolerability profile reads broadly similar to the class

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u/hedda_ekstrom22 points·1 months ago

daily dosing changes adherence in both directions

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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