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c/newbiequestions·posted 5 months ago by u/saskia_bakker

anyone else notice what is kicking in around week 86

Question The Quiet One ×5 Receipts ×1

anyone else notice what is kicking in around week 86. This is a description of what happened to me and not a plan for anybody else.

Wrote the concentration on the vial after reading it here. Have never once had to reconstruct it from memory since.

I confused two very similar words on my first order and asked here, expecting to be mocked. Three people explained it properly instead.

Tell me where this is wrong. That is the useful part of posting it.

2,072 up / 72 down97% upvoted53 commentsid uqjxjb28 Feb 2026

53 comments

17 in this archive, depth 4

best — the order this archive was captured in

u/low_appetite_lisa284 points·5 months ago

Concentration is mass over volume, and a U-100 syringe reads 100 units per millilitre. Those two facts are the whole of the arithmetic this board keeps explaining.

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u/gentle_correctionMOD157 points·5 months ago

Removed the specific dose recommendation. Describe what you did; do not tell a new member what to take.

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u/ferran_laurent129 points·5 months ago

Concentration is mass over volume, and a U-100 syringe reads 100 units per millilitre.

Agreed, and for anyone finding this later: that is the normal experience, not a warning sign.

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u/trialwatch_theotrial nerd173 points·5 months ago

Agreed — week two with nothing on the scale is so common it should be in the sidebar. It probably is.

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u/renal_outcomes_rnephro-curious45 points·4 months ago

Careful — that is a dosing recommendation dressed as an anecdote, and this board removes those.

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u/greta_perrin153 points·5 months ago

Is this your first step up or the starting dose?

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u/dario_bakken52 points·5 months ago

no question is too basic here, that is the entire point of the board

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u/gentle_correctionnice about it18 points·4 months ago

week two with nothing happening is normal

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u/nordic_pricing16 points·5 months ago

no question is too basic here, that is the entire point of the board

dario_bakken has explained this better than the wiki does, which is saying something.

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u/adaeze_cabrera82 points·4 months ago

Titration is a tolerance ladder. Each step exists so the gastrointestinal effects settle before the next increase, which is why the intervals are what they are.

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u/liver_enzyme_liz63 points·4 months ago

The five things that would have saved me the most time in month one.

One: the first month is a tolerance check, not a results phase. Two: appetite usually changes before the scale does, so watch that instead. Three: write the concentration and the date on the vial the moment you reconstitute anything. Four: the loud posts are not the middle of the distribution. Five: nobody here — including whoever answers most confidently — is your clinician.

None of that is advice about what to take. It is the shape of the first few weeks, which is what I actually wanted and could not find.

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u/britt_zamora63 points·4 months ago

Titration is a tolerance ladder.

This is the answer. Everything else in the thread is elaboration on it.

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u/solene_abubakar48 points·4 months ago

This is the answer.

Slight disagreement with this bit only, because a beginner reading it might take it as a plan rather than a description.

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u/rekha_teixeira70 points·4 months ago

What does the wiki page on this say — genuinely asking, not deflecting?

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u/lina_adebayo54 points·4 months ago·edited

My first question here was genuinely basic and it now shows up in search for other people asking it.

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u/ines_krastev12 points·4 months ago·edited

The injection was scarier in my head than in reality. It took about ten seconds and I felt slightly silly afterwards.

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u/rina_bergstrom4 points·4 months ago

pens and vials are the same molecule with different logistics

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About c/newbiequestions

The deliberately gentle community. Every question that gets an eye-roll elsewhere lives here: what does titration mean, why do I feel nothing in week two, is this normal, what is bac water, what is a COA. Rudeness is removed faster than bad questions.

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