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[Long Term] found my lowest effective dose by going down, not up

Long Term The Quiet One ×4 Slow Clap ×3

Right, the lowest effective dose question again, but with numbers this time.

I have 10 data points over 22 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 57, not week 11. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

1,653 up / 600 down73% upvoted37 commentsid 16a8bt18 Jul 2026

37 comments

23 in this archive, depth 4

best — the order this archive was captured in

u/taper_off_tabithaMOD218 points·11 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/nadia_nascimentoOP-30 points·11 days ago

Flair changed to match the content.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/zeynep_mbeki1 point·11 days ago

the 1.7mg dose works fine for 29 weeks of the month

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[deleted]88 points·11 days ago

[deleted]

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u/old_account_202355 points·10 days ago

[deleted]

Yes, exactly this, and it is the bit that took me 69 weeks to accept.

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u/nadia_nascimentoOP23 points·10 days ago

How long at maintenance?

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u/dario_petrescu27 points·10 days ago

food noise returns but not always immediately

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u/marisol_frisk8 points·10 days ago

food noise returns but not always immediately

Disagree on that part. 97.4% and 98.3% on the same vial is normal.

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u/elise_ramos111 points·10 days ago·edited

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/nadia_nascimentoOP45 points·9 days ago

lowest effective dose is lowest effective dose, find it or stay higher

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u/sarcopenia_watch155 points·9 days ago

dose-stretching experiences welcome, dose-stretching instructions are not

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u/marisol_frisk105 points·11 days ago

I am going to push back on this slightly.

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u/incretin_ivypharmacology74 points·11 days ago

regain after taper is expected, plan for it

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u/honest_syringe56 points·10 days ago·edited

Titration speed is a side-effect dial far more than an efficacy dial.

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u/rafael_krastev17 points·10 days ago·edited

Mechanistically the bit that matters is dose stretching. It explains most of the early profile and a decent chunk of the outcome.

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u/priya_weiss10 points·9 days ago

That is net peptide content, not purity. Different number, different meaning.

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u/sena_balogun45 points·11 days ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/liv_kuipers28 points·10 days ago

nobody posts about this part and it is the longest part

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u/anders_vermeulen14 points·10 days ago

nobody posts about this part and it is the longest part

Yes, exactly this, and it is the bit that took me 46 weeks to accept.

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u/omar_eriksen23 points·10 days ago

How long at maintenance?

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u/arne_ndiaye13 points·11 days ago

Yeah, maintenance is the boring part and the important part.

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u/elise_ramos3 points·11 days ago

The plateau is real and boring. 83 weeks at the same weight, then movement again. Patience was the intervention.

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u/fatima_yildiz7 points·11 days ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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About c/maintenancephase

The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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