unpopular opinion: most of what gets said here about integration is guesswork
unpopular opinion: most of what gets said here about integration is guesswork. Not a hot take, just something I have not seen said plainly here. Chased a ghost peak for three weeks. It was the plumbing. It is always the plumbing. A shoulder that does not baseline-resolve cannot be quantified honestly. You can report…
System suitability — repeat injections, tailing factor, plate count, RSD on area — is what tells you the instrument was fit for the measurement that day. Without it, the purity figure is unanchored.
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ghost peak, check the plumbing first, it is always the plumbing
What did system suitability look like on that sequence?
Carryover from a previous high-concentration injection looks exactly like a small impurity. The blank injection is four minutes and it removes the ambiguity entirely.
Ran a blank after a high-concentration injection and found the carryover I had been calling an impurity.
Disagree. Inter-lab spread of a point or two on this assay is ordinary and calling it a discrepancy misleads people.
Cosigning the wavelength point. Half the disagreements in this board are two people looking at different detectors.