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c/glp1women·submitted 1 year ago by u/sterile_field_steph

insulin resistance — my 21-week log, condensed into one table

Discussionbranch of 7 comments

insulin resistance — my 21-week log, condensed into one table. Making the case below, and I expect to lose some of it in the comments. Brought the cycle-annotated log to an appointment and it changed the conversation completely. Went looking for trial data on the specific question asked here and found the population…

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7 comments, started 1 year ago
u/elin_lindqvist24 points·1 year ago

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.

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u/ismael_chukwu31 points·1 year ago

PCOS is a diagnosis, not a description, and it matters which you mean

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u/bastian_moreau35 points·1 year ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

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u/georgi_haddad25 points·1 year ago

Push back: PCOS as a diagnosis and insulin resistance as a finding are not interchangeable, and the thread is using them as one.

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u/lipid_panel_larrybloodwork11 points·1 year ago

the trials were not designed to answer most of the questions asked here

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u/bastian_aalto15 points·1 year ago

fertility can change with weight loss and that surprises people

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[removed]11 points·1 year ago

[removed by moderator]

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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