5 months in and PCOS is still the thing I get wrong
5 months in and PCOS is still the thing I get wrong. Posting the boring middle of the process, because the internet is full of the start and the end and nothing else.
Numbers, in the order they matter: 5 months.
The questions that leave this board, and where they go.
Anything about pregnancy, planning a pregnancy, or contraception efficacy goes to a clinician. Absorption questions about a specific oral product go to a pharmacist, who can look it up in minutes. Fertility changes with weight loss are well described and worth raising with whoever prescribes, in advance rather than afterwards.
What stays here usefully: experience, cycle-annotated patterns, the vocabulary, and the collective knowledge that a research gap exists. That is a genuinely valuable set of things and it is a smaller set than people arriving here expect. Nothing on this board is medical advice and on this board that is not a formality.
Why the evidence base here is thin, which is not your imagination.
The major trial programmes were designed around endpoints that do not answer most of the questions this board asks: cycle interactions, contraception, fertility, perimenopause. The populations were not enrolled to answer them and the endpoints were not chosen to measure them.
So when you search and find nothing, that is usually the actual state of the literature rather than a failure of searching. What follows practically: be precise about your question, take the pharmacology parts to a pharmacist who can look up product-specific information, and treat confident answers on this board — including the ones that agree with you — with more caution than usual.
Happy to answer the boring questions. Those are usually the ones worth asking.
best — the order this archive was captured in
Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.
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the trials were not designed to answer most of the questions asked here
Trial populations for the major programmes were not designed around the questions this board asks most often, which is why the evidence base here is genuinely thinner rather than merely harder to find.
I would not read one person’s cycle-linked experience as a general pattern. The variation here is enormous.