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c/glp1muscle·submitted 1 year ago by u/zaid_roos

[Results] 39 weeks on 12.5mg, full numbers, ask me anything boring

Resultsbranch of 9 comments

Reporting in. 39 weeks on 12.5mg, full numbers, ask me anything boring. 39 weeks and 12.5mg — those are the numbers, and they are the ones I am willing to defend. Three scans over eighteen months, same machine, same conditions. Only the third one made the first two interpretable. What the evidence actually supports,…

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9 comments, started 1 year ago
u/zaid_roos0 points·1 year ago

Strength retention is an imperfect but free longitudinal proxy: it is affected by neural factors and by being in a deficit, so it tracks tissue change loosely rather than exactly.

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u/yara_mensah-8 points·1 year ago

Hydration status and fasting state affect the lean mass estimate. Standardising both is the difference between a comparison and a coin toss.

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u/trialwatch_theotrial nerd1 point·1 year ago

DEXA has a real error margin and people quote it to one decimal

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u/line_demir1 point·1 year ago

Tracked grip strength and three lifts monthly. Cheaper than scanning and directionally the same answer.

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u/karl_fischer_kev1 point·1 year ago

grip strength and lift numbers are cheap longitudinal markers

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u/zaid_roosOP1 point·1 year ago

What is protein intake actually looking like, measured rather than estimated?

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u/diego_iyer1 point·1 year ago

losing weight slower does not automatically preserve more lean mass

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u/zaid_roosOP1 point·1 year ago

Two scans on the same machine 2 months apart. Lean mass held better than I expected and the lifts told the same story for free.

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u/draw_up_dizzy1 point·1 year ago

protein and resistance training, that is the entire intervention

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Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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